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* = applied session ! = JSM meeting theme
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Keyword Search Criteria: Adaptive design returned 40 record(s)
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Sunday, 07/31/2016
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The Utility of Conditional Autoregressive (CAR) Models for Modeling Efficacy of Molecularly Targeted Agents in Early-Phase Trials
Thomas Braun, University of Michigan
2:05 PM
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Two-Stage Design for Phase I/II Cancer Clinical Trials Using Drug Combinations of Cytotoxic Agents
Mourad Tighiouart, Cedars-Sinai Medical Center; Quanlin Li
2:25 PM
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An Overview of Innovative Statistical Designs for Point-of-Care Comparative Effectiveness Trials
Mei-Chiung Shih, Palo Alto VA Health Care System/Stanford University
2:30 PM
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A Decision-Theoretic Phase I-II Design for Ordinal Outcomes in Two Cycles
Juhee Lee, University of California at Santa Cruz; Peter F. Thall, MD Anderson Cancer Center; Peter Mueller, The University of Texas at Austin; Yuan Ji, The University of Chicago
3:05 PM
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Continuous Event Monitoring via a Bayesian Predictive Approach
Jianing Di, Janssen R&D; Daniel Wang, Janssen R&D; Robert Brashear, Janssen R&D; Vlad Dragalin, Janssen; Michael Krams, Janssen R&D
4:45 PM
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Monday, 08/01/2016
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A Bayesian Adaptive Design in Cancer Phase I Trials Using Dose Combinations in the Presence of a Baseline Covariate
Sungjin Kim; Mourad Tighiouart, Cedars-Sinai Medical Center; Marcio Diniz, Cedars-Sinai Medical Center
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Bayesian Adaptive Designs Using Copula-Type Models in Phase I Cancer Trials Using Drug Combination
Galen Cook-Wiens, Cedars-Sinai Medical Center; Mourad Tighiouart, Cedars-Sinai Medical Center; Marcio Diniz, Cedars-Sinai Medical Center; Andre Rogatko, Cedars-Sinai Medical Center
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Bayesian Adaptive Design for Delayed Binary Response Dose-Finding Studies
Xiaobi Huang, Sanofi; Haoda Fu
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Bayesian Response-Adaptive Covariate-Adjusted Randomization Design for Clinical Trials
Jianchang Lin, Takeda; LiAn Lin, Merck Research Laboratories; Serap Sankoh, Takeda; Fang Yang, Vertex Pharmaceuticals; Guohui Liu, Takeda
8:50 AM
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Bayesian Adaptive Design for Trials with Delayed Binary Outcome Using Historical Control Data
Nusrat Harun, Cincinnati Children's Hospital ; Mi-Ok Kim, Cincinnati Children's Hospital Medical Center; Chunyan Liu, Cincinnati Children's Hospital
9:35 AM
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Risk Analysis on Using Surrogate Endpoint at Interim Analysis
Ziqian Geng, AbbVie; Bo Fu, AbbVie; Alan Hartford, AbbVie; Jun Zhao, AbbVie
10:05 AM
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Adaptive Design in Large-Scale Sample Surveys: Different Perspectives
Peter Miller, U.S. Census Bureau; Marilyn Seastrom, National Center for Education Statistics; Paul Biemer, RTI International
10:35 AM
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A Simple Bayesian Design to Identify Maximum Tolerated Dose Contour for Drug Combination Trials
Liangcai Zhang, Rice University; Ying Yuan, MD Anderson Cancer Center
2:20 PM
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Tuesday, 08/02/2016
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Alternative Goals for Adaptive Survey Design
Peter Miller, U.S. Census Bureau
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Case Study: How Promising Is the VALOR Trial for the Future of Adaptive Designs?
Yannis Jemiai, Cytel
10:55 AM
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Regulatory and Practical Considerations for an Adaptive Trial in the Context of Evaluating a Combination Product: An Example Using Two Human MAbs to Prevent Recurrence of CDI
Kenneth Koury, Merck Research Laboratories; Robert Tipping, Merck Research Laboratories
11:15 AM
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Responsive Design: Side Effect Reduction of Prior Information on Survey Design
Abdellatif Demnati, Retired
2:05 PM
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Practical Experiences with Adaptive Dose-Escalation Designs in Early-Phase Oncology Trials
Inna Perevozskaya, Pfizer
2:05 PM
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Adapting Responsive Design Strategies in a Recurring Adult Literacy Assessment
Minsun Riddles, Westat; Tom Krenzke, Westat
2:20 PM
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Application of Adaptive Designs to Optimize a Compound Development Program
Yevgen Tymofyeyev, J & J PRD
2:25 PM
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Case Studies for Biologics Trials in Very Rare Diseases
John Scott, FDA
2:35 PM
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Toward an Adaptive Design for the Survey of Doctorate Recipients
Michael Yang, NORC at the University of Chicago; Wan-Yinig Chang, National Science Foundation; Karen Grigorian, NORC at the University of Chicago
2:35 PM
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Interim Timing in Adaptive Two-Stage Dose-Finding Studies: What Happens to the Expected Benefit?
Tobias Mielke, ICON PLC
2:45 PM
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Implementing Adaptive Design on a Longitudinal Survey of At-Risk Youth:Empirical Evidence Based on a Deep-Dive Analysis
Hanzhi Zhou, Mathematica Policy Research; Jillian Stein, Mathematica Policy Research
2:50 PM
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New Perspectives on Sampling Rare Populations
Emanuela Furfaro, University of Milano-Bicocca
3:20 PM
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Wednesday, 08/03/2016
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A Web Application for Optimal Selection of Adaptive Designs in Phase I Oncology Clinical Trials
Sheau-Chiann Chen; Yu Shyr, Vanderbilt University
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Predicting and Preventing Break-Offs in Web Surveys
Felicitas Mittereder, University of Michigan
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Estimation After Adaptive Population Enrichment Design
Vlad Dragalin, Janssen
8:35 AM
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Unblinded Sample Size Re-Estimation in Bioequivalence Trials with Small Sample Sizes
Sam Hsiao, Cytel; Lingyun Liu, Cytel
8:35 AM
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Impact of Adaptive Design on Optimization of Pharmaceutical Portfolios
Zoran Antonijevic
8:35 AM
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Predicting and Preventing Break-Offs in Web Surveys
Felicitas Mittereder, University of Michigan
8:55 AM
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Challenges and Experience in Designing Small Clinical Trials
Christopher Coffey, University of Iowa
9:15 AM
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Adaptive Enrichment with Subpopulation Selection at Interim
Xiang Ling, FDA/CDER; Sue-Jane Wang, FDA; Kun Jin, FDA/CDER; Hsien-Ming James Hung, FDA
9:35 AM
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Arm Dropping in Clinical Trials: An In-Depth Look at Statistical Considerations and Implications
JonDavid Sparks, Eli Lilly and Company; Brian Millen, Eli Lilly and Company; Qi Zhang, Eli Lilly and Company
10:05 AM
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How Many Birds Can Be Killed with One Stone? The KEYNOTE-001 Experience
Cong Chen, Merck; Nicole Li, Merck; Jin Zhang, Merck
2:05 PM
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Using Adaptive Designs to Avoid Selecting the Wrong Arms in a Comparative Effectiveness Trial
Byron Gajewski, University of Kansas Medical Center
2:50 PM
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Thursday, 08/04/2016
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Efficient Study Designs in Clinical Research
Steven Julious, University of Sheffield
8:35 AM
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Experimenting with Contact Strategies to Aid Adaptive Design in Business Surveys
Cha-Chi Fan, U.S. Census Bureau; Alfred D. Tuttle, U.S. Census Bureau; Joshua Langeland , U.S. Census Bureau; Erica Marquette, U.S. Census Bureau; Aryn Hernandez, U.S. Census Bureau; Stephanie Coffey , U.S. Census Bureau; Jennifer Beck, U.S. Census Bureau
9:15 AM
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Survey of Income and Program Participation Case Prioritization Experiment Results
Gina Walejko, U.S. Census Bureau; Allison Zotti, U.S. Census Bureau
9:35 AM
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Comparison Beyond Power: Sample Size Re-Estimation vs. Group Sequential Design
Lei Shu, Astellas Pharma; Charles Liu, Astellas Pharma; Matt Rosales, Astellas Pharma
11:05 AM
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